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Understanding Protein-Based Medication Storage A comprehensive 2023 Cochrane systematic review on insulin thermal stability provides additional context relevant to all protein-based injectable medications, including GLP-1s

However, certain circumstances may warrant testing including pre-existing liver or kidney conditions where monitoring organ function during therapy provides appropriate oversight, specific health concerns that might benefit from objective biomarker assessment, desire to objectively measure oxidative stress markers or glutathione status before and during therapy, and medical conditions requiring monitoring for safety reasons

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Wang C, Feng Q, Lu H et al (2024) Metabolic regulating enhanced immunological activating nanocomposites for tumor microenvironment normalization and immunotherapy