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Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways

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2019;9(11):e031431

If you see any floating particles or if the solution remains cloudy after several minutes of gentle swirling, it may indicate a problem with the peptide or potential contamination