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Participants received once-weekly injections of retatrutide at either the 9mg or 12mg dose, or a placebo, over 68 weeks
conducted a pre-specified cardiovascular meta-analysis that included all seven randomized controlled trials with a duration of at least 26 weeks from the SURPASS trials [61]
It violates the spirit of sport (this definition is outlined in the Code)
Liraglutide can cause side effects, including nausea, vomiting, and potential serious risks such as pancreatitis and gallbladder problems, and is not right for everyone
Based on Phase 2 trial data (Jastreboff et al., NEJM , 2023), the most commonly reported adverse effects of retatrutide include: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (most frequent, particularly during dose escalation) Injection site reactions: Redness, bruising, or mild discomfort Decreased appetite: Generally considered a therapeutic effect but can contribute to nutritional deficiency if severe Increased heart rate: Observed with glucagon receptor agonism
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