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While tirzepatide has a more potent effect on blood sugar control and weight loss, it also has a higher incidence of gastrointestinal side effects and hypoglycemia

Some studies have shown that oxidative stress may be present even when a standard semen analysis appears normal

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Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA. The Lancet

Instead, modified activity that avoids aggravating movements while maintaining baseline function typically produces better outcomes