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Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

To begin, we assessed overall germline sizes at the L4 stage, which were comparable in wild-type, fbf-1 fbf-2 and puf-3 puf-11 , but much smaller in quadruple mutants (Figure 4A-D)

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Glutathione, a tripeptide composed of -glutamic acid, cysteine and glycine is quantitatively the most important low-molecular-weight (non-protein) thiol in tissues[6, 9, 10]