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The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family

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Therefore, binding of the nanobody does not completely fix gB in a single position as in the case of the stabilizing mutations, as areas such as the transmembrane region remain flexible, but rather seems to prevent the principal conformational changes required for fusion

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