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Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis

T., Wise, P

Int J Food Sci Technol

doi: 10.1038/s41598-022-15839-7 9 JencksDSAdamJDBorumMLKohJMStephenSDomanDB

In the reaction, formation of cysteine hercynylsulfoxide from L-histidine is catalyzed by FvEgt1, as the same as that in other fungi, while liberation of EGT from cysteinyl hercynylsulfoxide is catalyzed by FvEgt2 and FvEgt3 simultaneously

Although low-grade inflammation has been evidenced in the depressed patient population and anti-inflammatory drugs showed encouraging results in pilot studies, anti-inflammatory drugs are not indicated as monotherapy or add-on treatment for depression yet (see for review [138])