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Willow , for example, ran ads encouraging patients to cancel their gym membership and promised rapid weight lossmessaging that directly contradicts clinical guidelines and feeds into unhealthy narratives (they also prescribe to patients regardless of BMI)

Despite the shared mechanisms of action, these clinical approaches vary considerably in development strategy and trial design

Some patients use GLP-1 therapy preemptively after surgery to enhance early satiety and maximize weight loss, though this requires closer medical oversight

Trends Endocrinol Metab 2018;29:23848.ArticlePubMed 38

To get there, we need to systematically study smaller doses of real GLP-1 therapies in people with different conditions

Nature 2002