Black realised the only way to find out was to test out his idea by developing a histamine antagonist in the same way as he had previously done with propranolol
When combined with medicines such as metformin or insulin, there is a theoretical risk of hypoglycaemia (low blood sugar), and close monitoring would be required
Importance of Medical Supervision Because GLP-1 affects multiple systems, careful monitoring by a healthcare provider is essential
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J Stud Alcohol Drugs 85:510 Brunchmann A, Thomsen M, Fink-Jensen A (2019) The effect of glucagon-like peptide-1 (GLP-1) receptor agonists on substance use disorder (SUD)-related behavioural effects of drugs and alcohol: a systematic review
Welcome to food noise: A constant, often exhausting internal monologue about food that, for some, plays on loop from breakfast to bedtime