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Hepsin is crucial in protecting against APAP-induced liver injury by regulating gap junctions and reducing oxidative stress

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Polycyclic aromatic hydrocarbons (PAHs) found in cigarette smoke, for example, have been shown to decrease the activity of P450 enzymes, leading to a decrease in SAMe production and impaired DNA methylation

doi: 10.2174/0109298673300496240416114827 151