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It may come from preclinical or in vitro data

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[DOI] [PubMed] [Google Scholar] 22.Gogel AC, et al

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The combination of vancomycin, neomycin sulfate, metronidazole, ampicillin, and other broad-spectrum antibiotics can alleviate choline-induced atherosclerosis in mice, and the mechanism may be related to the inhibition of choline conversion to TMA, the reduction of TMAO levels, and the inhibition of macrophage foaming

39 , e3673 (2023)