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This helped to show that NNMT is a key target in metabolic research. Neelakantan and colleagues then expanded research involving small-molecule NNMT inhibitors

People taking them are "becoming lab rats," said Adam Taylor, a professor of anatomy at Lancaster University in the U.K

There is no UK Summary of Product Characteristics (SmPC) for retatrutide, and no authorised clinical dosing or reconstitution guidance exists

Additionally, it is contraindicated in patients with megaloblastic anemia due to vitamin B12 deficiency without concurrent folate deficiency

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