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Metformin and/or low dose radiation reduces cardiotoxicity and apoptosis induced by cyclophosphamide through SIRT-1/SOD and BAX/Bcl-2 pathways in rats

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"The adipose tissue (AT) expandability hypothesis explains that the individual capacity to appropriately store energy surplus as fat within the AT prevents the toxic deposition of lipids in other organs, such as the pancreas. Looping back to the role of the brain in obesity, I would move one level higher in the cascade of downstream effects - to the central regulation of hedonic appetite and the wiring of the reward system, overexpressed obesogenic genes within the CNS, and the role of ultra-processed food

Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study

Elevated levels of fractalkine expression and accumulation of CD16 + monocytes in glomeruli of active lupus nephritis

Todorova V, Vanderpool D, Blossom S, Nwokedi E, Hennings L, Mrak R, et al