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The estimated treatment ratios of the mean AUC 0 of cagrilintide compared with the normal hepatic function group were 0.99 (90% CI, 0.891.11) for the mild hepatic impairment group, 1.01 (90% CI, 0.911.12) for the moderate hepatic impairment group and 1.11 (90% CI, 0.961.30) for the severe hepatic impairment group

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The first application of the peptide was given immediately after the burn-injury

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They also have an impact on NAMPT levels 6 , which fluctuate to meet cellular NAD+ demand

[DOI] [PMC free article] [PubMed] [Google Scholar] [112].Maeda K, Otomo K, Yoshida N