3.2.4 Ferroptosis and amyotrophic lateral sclerosis ALS is a lethal NDD characterized by progressive degeneration of upper and lower motor neurons in the cerebral cortex, brainstem, and spinal cord, leading to skeletal muscle atrophy, weakness, weight loss, dysarthria, dysphagia, paralysis, and ultimately death from respiratory failure (Urano et al., 2025)
Owing to their lack of efficacy on cardiorenal outcomes, dipeptidyl-peptidase (DPP-4) inhibitors are only recommended to control hyperglycemia
Pre-treatment with curcumin ameliorates cisplatin-induced kidney damage by suppressing kidney inflammation and apoptosis in rats
In formula form, you might see it written as: TDEE = BMR + activity + TEF (and a small amount for other processes)
Pregnenolone gets converted into: DHEA Estrogen compounds Progesterone compounds Cortisol Related Post: Cortisol Imbalance and How to Support Your Adrenals with Mast Cell Activation Syndrome (MCAS) Since we are talking about estrogen dominance, well focus on estrogen and progesterone
Gentle skincare : Use mild, non-irritating cleansers and moisturizers