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Badenhorst T, Svirskis D, Merrilees M

AGEs are proteins or lipids that glycate and bind to the Receptor for Advanced glycation end-products (RAGE) and mediate inflammatory pathways and reactive oxygen species (ROS) (8)

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In lung cancer models, lutein was found to induce apoptosis by modulating PI3K/Akt signaling, effectively inhibiting Akt to trigger cancer cell death while sparing normal cells ( 3.2.4 Carotenoids: oxidative stress and miRNA networks Lycopene modulates oxidative stress-responsive miRNAs in prostate cancer through antioxidant pathways

Khot, S., Tackley, G., & Choy, E

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