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Cyanocobalamin, a slightly toxic, synthetic form, is especially dangerous to pernicious anemia patients
However, there are no clinical studies examining this combination
Obesity Pharmacotherapy: Current Perspectives and Future Directions, Misra M., Journal (Current Cardiology Reviews, Volume 9, Issue 1, February 2013, Pages 3354)
A lack of Vitamin B12 can cause numbness and tingling, and problems with thinking
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[3] The speed of response depends on multiple factors including the severity and duration of deficiency, the presence of neurological complications, and individual metabolic differences
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