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Yousif et al., 2016) showing a marked improvement in the histopathological and histochemical features along with inflammatory mediators without measuring redox, apoptotic, and kidney function parameters

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To delve deeper into the potential role of microbiome led dysbiosis in distinguishing between tumor patients and healthy patients, further investigation is required with an emphasis on clinical validations and elucidation of underlying mechanisms

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Among the cohort studies, 2 scored three and five points, indicating low-quality studies with high and moderate risk of bias, respectively