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Some early data hints at modest changes, but this is not firmly settled, and B12 depletion is far more strongly linked to other medications (such as metformin) than to semaglutide
Your doctor or pharmacist can point out where the expiration date is printed on your medication
Saxenda helps with weight loss in three main ways: It reduces appetite, so you feel less hungry It slows the emptying of your stomach, so you feel full for longer These effects together help lower your overall calorie intake Warnings BOXED WARNING: Risk of thyroid tumors Based on animal studies, liraglutide (the active ingredient in Saxenda) caused thyroid C-cell tumors in rats and mice
doi: 10.1097/MED.0000000000000217 38 HinnenD
21, 2025, the FDA determined that the semaglutide shortage is over, giving compounding pharmacies a deadline for ceasing the distribution of compounded versions of injectable semaglutide that are essentially identical to FDA-approved versions (e.g., Wegovy and Rybelsus)