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Ozempic is a once-weekly injectable medication or once-daily pill FDA-approved for the treatment of type 2 diabetes

Diabetes-induced cardiomyocyte passive stiffening is caused by impaired insulin-dependent titin modification and can be modulated by neuregulin-1

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N-acetylcysteine, NAC

A total of 177 natural products with greater potential for AD treatment were screened by mapping the target gene set of each natural product to the constructed network, yielding 177, 103, and 29 natural products from Most Studied Pathways, Gene-Associated Pathways, and Popular Pathways, respectively (Additional file 1: Table S7)

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