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[1] Bi-Amino Injections clinical rationale draws on pharmacokinetic evidence that intravenous arginine produces a sharp plasma peak followed by biphasic clearance, whereas citrulline bypasses splanchnic arginase activity, undergoes efficient renal conversion back to arginine, and sustains substrate availability for nitric-oxide synthase several hours beyond the initial infusion

Direct injection creates foam, denatures surface peptide molecules through mechanical shear, and reduces overall potency by 510% in a single reconstitution step

doi: 10.1016/j.tice.2022.102000, 44

I also have a piece on natural soap colorants listing different ingredients based on color

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