Daniel Drucker, a leading researcher in the field, suggests that GLP-1 agonists may reduce harmful inflammation through multiple mechanisms, including direct immune modulation and neuroinflammation regulation
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Clinical studies have shown oral semaglutide to have superior efficacy to placebo and to a number of oral and injectable active comparators representative of common drug classes (DPP-4 inhibitors, other GLP-1RAs, SGLT2is), with a safety and tolerability profile consistent with the GLP-1RA class
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K.et al (2018b)
