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10.1016/0167-4781(92)90036-Y 33

In mouse and cell models of amyotrophic lateral sclerosis (ALS), IGF1 also strongly protects mitochondria from apoptosis and upregulates mitophagy, as evidenced by a decrease in the p62 level and an increase in the LC3-II level (Wen et al., 2019)

This creates a synergistic effect with the carnitine complex: EGCG mobilizes more fatty acids from adipose tissue, and the five carnitine forms transport those mobilized fatty acids into mitochondria for beta-oxidation

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