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showed that in the absence of DNA, a member of the basic/helix-loop-helix/zipper family of DNA-binding proteins, transcription factor Max, is rapidly digested by several endoproteases, indicating an open and flexible structure of the protein in the unbound form (Cohen et al., 1995)

Nat Neurosci (2017) 20(12):175260

N., Song, Y., Chen, W., Wang, G., Edden, R

These signaling processes are analyzed in vitro to evaluate receptor activation, ligand affinity, and downstream intracellular communication