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The effect of pressures on microorganisms is generally understudied compared to other extreme conditions due to sampling of high-pressure environments on Earth being technically challenging and the requirement for specialised culturing facilities (Oger and Jebbar, 2010)

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Hou C, et al

While a decrease in serum urea level and an increase in serum creatinine level were detected in the MTX group, WPC administration reversed these results up to control group levels

The Journal of pharmacology and experimental therapeutics