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Stephens FB, Wall BT, Marimuthu K, Shannon CE, ConstantinTeodosiu D, Macdonald IA, Greenhaff PL: Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans

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The 20.7% figure comes from the STEP-UP trial of 1,742 adults living with obesity, published in NEJM in 2025

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