19(5 pt 1):831836
In short, anything that causes injury to cochlear hair cells or nerve fibers- from loud noise to microvascular or inflammatory disease- can produce hearing loss and often generates phantom sound perceptions (tinnitus) as the auditory system tries to compensate for lost input
Signs and symptoms Loose joints Joint pain Stretchy, velvety skin Fragile skin Abnormal scar formation Complications Aortic dissection Joint dislocations Scoliosis Chronic pain Early osteoarthritis Management Obstetrical anesthesia Difficult management, requires multidisciplinary effort High risk of preterm labor, uterine rupture, and hemorrhage Neuraxial anesthesia is relatively contraindicated, may need general anesthesia If vascular subtype recommendations are termination of pregnancy or Cesarean section before 32 weeks Keep in mind Avoid ambulatory surgery in EDS patients Be aware of typical EDS-related emergency-like situations such as difficult airway status, bleeding risks, and organ rupture in specific subtypes Suggested reading Malfait F, Francomano C, Byers P, et al
The list is extensive and includes both specific compounds and catch-all categories
Dont like needles
Vitamin B12 deficiency in the brain leads to dna hypomethylation in the TCBLR/CD320 knockout mouse
