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142 , this model includes three human genetic mutations, APP Swedish, PSEN1 M146V, and tau P301L, that lead to the formation of both amyloid plaques and tau tangles
Importantly, no increase in total plaque area was observed in mice on the BB supplemented diet in which gut microbes was suppressed by the antibiotics cocktail (+ABS)
2.3.9 Clinical chemistry Serum concentrations of the following parameters were determined photometrically using the automated analyzer Indiko Plus (Thermo Fisher Scientific GmbH, Waltham, USA): albumin, cholesterol, glutamate dehydrogenase (GLDH), total protein, urea, alkaline phosphatase (ALP), and alanine aminotransferase (ALT)