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Kinetics and persistence research enabled by long acting analogue design Long acting analogues are frequently used in research settings because they can support extended exposure paradigms and persistence studies without requiring constant preparation changes

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13, 2022, FDA approved AMVUTTRA (vutrisiran), an RNAi therapeutic administered via subcutaneous injection once every three months (quarterly) for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults