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PMID: 33970480

Melatonin has been used in clinical trials to increase embryo quality in women undergoing IVF, and it has been used in several studies with women with PCOS to normalize hormones and increase egg quality.[ref][ref][ref][ref] Melatonin also may play a role in keeping the mothers body from rejecting the fetus.[ref] Related Article: Genetic links to infertility for women Gut Microbiome: It makes sense that melatonin would affect gut microbes since it is both an antioxidant and an immune modulator

Once stabilized, PINK1 phosphorylates Mitofusin 2 (Mfn2) and ubiquitin, facilitating the recruitment of the E3 ubiquitin ligase Parkin to the OMM (58)

That last point carries more weight than most people realize

Many people assume their symptoms are just stress, aging, or burnout, when low B12 may be part of the picture

Your body's testosterone levels and vitamin B connection becomes more important as you age, especially after 60 when hormone production naturally slows down