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Rapid weight loss from any cause, including pharmacotherapy, can increase the risk of gallstone formation in patients with intact gallbladders

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6 (calculated mass=4,224.6 Da, observed mass=4,224.0 Da)

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Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor Tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative study