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(1994) have shown that in the serum of CKD patients MDA level is 42% higher, and in patients on HD 76% higher, as compared with the control group

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An additional critical layer of pathophysiology involves alcohol-induced gut barrier dysfunction and microbiota dysbiosis, which promotes endotoxin translocation to the liver, thereby exacerbating immune-mediated inflammation and driving progression from steatosis to hepatitis and fibrosis (Wang et al., 2010)

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