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Mol Pharmacol (2005) 68(3):84754

One of the first requirements is a clear scientific rationale explaining why the compound's mechanism of action or biological target may potentially provide a therapeutic benefit

The results obtained in the zwf1 strain further highlight the advantage of the oxidant recovery assay over the sole determination of steadystate OxD values as OxD[IMS] and OxD[cytosol] at steady state differed only slightly from the respective value in the wt

These cumulate in ladening of fatty deposits in the blood vessels with resultant vasoconstriction, excessive fluid retention, and sustained rise in blood pressure [22]

Our team has worked with research groups who stored reconstituted vials in laboratory freezers at 20C, assuming this would extend stability indefinitely

When indicated, cells were exposed to menadione sodium bisulfite or N -acetyl-l-cysteine (NAC