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Important safety considerations include contraindications in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, caution in those with a history of pancreatitis, increased risk of gallbladder disease, potential for acute kidney injury with dehydration, and possible worsening of diabetic retinopathy with rapid glycemic improvement

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Past medical history included allergies (pollen, ash, dust mite, n=1), milk hypersensitivity (n=1), mild anorexia nervosa (n=1), mild delay of acquisitions (n=1) and hypospadias (n=1)