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Efficacy of GLP-1 RA Approved for Weight Management in Patients With or Without Diabetes: A Narrative Review

Exercise can help stimulate bowel motility (especially helpful if constipation is an issue) and is a proven stress-reducer

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Most adults with a BMI over 27 and weight-related health conditions, or a BMI over 30, may qualify for GLP therapy

Furthermore, HFD in catch up growth rat models induces lipotoxicity in the intestinal L cells, increasing intestinal L cell apoptosis and reducing GLP-1 secretion [30]

You may already be familiar with semaglutide under the brand names Ozempic (for diabetes) or Wegovy (for weight loss), both of which are injectables