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This testing period covers the most vulnerable phase of embryonic development when cancer-causing substances would be most likely to produce abnormalities

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Additionally, while clinical guidelines for indicated use of GLP-1 RAs are rapidly changing as evidence for GLP-1 RA use evolves, the ethics of off-label use are particularly important to consider given the impact these shortages can have on access for patients who otherwise have a strong clinical indication to be on them

Other similar studies also back up this claim

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In early trials, treated patients experienced small reductions in body weight despite large improvements in triglycerides, HDL cholesterol, and adiponectin