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In case of breast cancer, several exosomal microRNAs (exo-miRs) such as miR-21, miR-105, miR-20b have been found to enhance EMT, chemoresistance, and immune evasion (126)
Acknowledgements The authors extend their appreciation to the Deanship of Research and Graduate Studies at King Khalid University for funding this work through a Large Research Project under grant number RGP2/580/45
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Limitations of conventional therapies Modern pharmacological strategies for GI disorders rely on drugs such as antacids, proton pump inhibitors (PPIs), H 2 receptor antagonists, anti-inflammatory agents, antibiotics, and laxatives
Understanding Drug Half-Life: Calculations, Curves, and Clinical Relevance Drug half-life (t) is a core concept in pharmacokinetics that shows up on every major examand in every rotation
The company's decision to advance both programs suggests confidence that the GLP-1/amylin dual pathway represents the future of obesity pharmacotherapy, with room for multiple formulations serving different patient preferences
