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In a study by Rammohan et al., a new series of aminochalcone and hydroxychalcone analogs were developed as DPP-4 inhibitors (98)

$130 Billion 1 Projected Market Size of GLP-1 therapies in 2030 10-20% Body Weight Reduction 4 Treatment Breakthrough 42% of U.S

doi: 10.1016/j.autrev.2008.04.004

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Central adiposity has been linked to a higher risk of progression to T2D by several studies, and loss of visceral adipose tissue is critical in the remission of prediabetes and prevention of T2D development