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Some people have also reported nausea, bloating, and abdominal discomfort after taking higher doses

Metformin also regulates apoptosis by downregulating Bcl-2 and Bcl-xL expression and upregulating Bax and Cytochrome expression (43)

Cancer metabolism is a factor that might be exploited as a potential therapeutic target for drug discovery also on how a cancer cell differs in its metabolism to that of a rapidly proliferating normal cell (Vander Heiden et al

Disclaimer: Compounded medications are not FDA-approved drug products

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