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BMC Bioinformatics 17 , 485 (2016)

Current consensus definition: Prevalence, etiology, and consequences

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It is reported that B7-H3 enhances chemoresistance of CRC cells by regulating the expression of cell division cycle 25A (CDC25A) through STAT3 signaling pathway in CRC cells (103)

Together, these results suggest that sleep and sleep deprivation bi-directionally can impact the molecular signalling pathways that regulate synaptic strength and control brain plasticity, supporting the hypothesis of a direct relation between cortical plasticity and sleep regulation ( Figure 4 )