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Dosing Frequency Drugs with short t (e.g., acetaminophen) = frequent dosing Long t (e.g., amiodarone) = spaced out dosing schedules 2

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Research published in studies examining synaptic density following Dihexa administration found elevated synaptophysin and PSD-95 expressionmarkers of presynaptic and postsynaptic densitysustained for 714 days after a single administration cycle

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Attenuation of this vasodilation effect in the absence of endothelium suggested an endothelium-dependent vasodilation effect of BPC 157