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This is potentially important, as there is some evidence pointing to a role for mitochondrial abnormalities in bipolar disorder although this remains controversial

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LPS: lipopolysaccharide;TFRC: transferrin receptor;ROS: reactive oxygen species

As noted in the LLC model, TNF levels in both serum and lung homogenates also demonstrated a clear induction in B16-F10-challenged Igf1r fl/fl mice, remaining unaltered in CreERT2 mice (Supplementary Fig

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