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Essential fatty acids Omega-3 and omega-6 fatty acids are polyunsaturated fatty acids (PUFA), meaning they contain more than one cis double bond (86)

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The frequent association and intricate relationship of UA with cardiovascular risk factors, such as arterial hypertension, type 2 diabetes, dyslipidemia, metabolic syndrome and chronic kidney disease (,) is the main reason for the ongoing debate and dilemma whether UA is a risk factor (causal relationship) or a risk marker (an associate of cardiovascular risk) for CVD

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Moreover, the levels of proteins associated with cell proliferation, migration, and angiogenesis (Slc38a2, Psph, Jagn1, and Rorb) were upregulated