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The glucagon-like peptide 1 analogue, exendin-4, attenuates the rewarding properties of psychostimulant drugs in mice

David LaMond, Medical Director, Blue Sky MD I often get asked about the secret to sustainable weight management and metabolic health

Finally, collecting biomedical as well as qualitative data allowed interpretation of subjective experiences in the context of changes in physical health parameters

Instead, you lost energy

Administered as a once-weekly subcutaneous injection, semaglutide works by mimicking the naturally occurring hormone GLP-1

Furthermore, we confirmed GLP-1MK-801-mediated target engagement with NMDA receptors in GLP-1-receptor-positive neurons in the arcuate nucleus using electrophysiological recordings of isolated NMDA receptor currents