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It differs from IGF-1 by additional 13 amino acids at the N-terminus and the substitution of arginine with glutamic acid at the 3rd position

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in addition, the expression of the SLC1A5 variant affected the levels of metabolites derived from glucose metabolism, including lactate and ribulose-5-phosphate, the intermediate metabolites in the PPP 16

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The values were within acceptable range (6-10) moles per gramme wet weight of liver consistent with those reported by Jakoby et al [6]

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