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Additionally, these mice exhibited reduced MMP and increased ROS levels in their oocytes, indicating mitochondrial dysfunction and oxidative stress imbalance

This improved response corresponded with an increase in intratumoral lipid peroxides and MDA suggesting that ferroptosis is the cell death mechanism responsible for the in vivo tumor clearance (Figure 5EF)

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Lifestyle Changes Exercise: Regular physical activity has been shown to increase glutathione levels and improve antioxidant defenses

Alternatively, (ii) medication (BPC 157 (10 g/kg, 10 ng/kg)) was given perorally in drinking water (0.16 g/mL, 0.16 ng/mL, 12 mL/rat/day)