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The reaction mixture was stirred continuously under a nitrogen atmosphere at room temperature for 3 days

Rotation of Injection Sites: Rotation of injection sites, such as the abdomen, thigh, or upper arm, is essential to prevent skin irritation and maximize absorption

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Subjects came to the clinic the day before dosing and fasted overnight for 10 h before dosing (water ad libitum was allowed until 1 h before dosing)

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