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Pentose Phosphate Pathway: Oxidative Phase The overall reaction of the oxidative phase of the pentose phosphate pathway is shown below: Glucose 6-phosphate + 2 NADP+ + H2O Ribulose 5-phosphate + 2 NADPH + 2 H+ + CO2 In the first step of the oxidative phase, glucose 6-phosphate is oxidized to 6-phosphoglucono--lactone, which is a lactone or cyclic ester (Figure 1)

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Article highlights: GLP-1 drugs increase risk of bone loss, osteoporosis, and osteomalacia Users of Ozempic, Wegovy, and Victoza show higher Gout and uric acid risk How to support your bone health and muscles with nutrition The list of adverse effects linked with the globally popular GLP-1 medications continues to grow

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Responsible interpretation of the evidence base is paramount in every consideration, as is the strict separation between documented research and any interpretation as a consumption recommendation