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it has a large Vd and appears to be taken up into tissues

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DEXA substudies across the class suggest somewhere between a quarter and a third of the loss can be lean mass, and the early retatrutide figure sits at the high end of that range, with the usual caveats about what DEXA actually measures

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We reasoned that keeping the dimeric structure intact might help us avoid all the extra bands in virus-treated cells that interfered with determining exactly where the reduced monomer might be otherwise located