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Regarding the first primary endpoint of change in heart failure-related symptoms and physical limitations from baseline to 52 weeks, semaglutide improved KCCQ-CSS in all diuretic subgroups, but the magnitude of improvement was greater in patients receiving loop diuretics compared to those not on loop diuretics, with an adjusted mean difference vs

protocols YG21113 and ZO23242) and performed in compliance with applicable animal welfare regulations

2025;20(1):e0317202

Additionally, some employers offer Noom as a sponsored benefit, making it free for eligible employees

2026), doi: 10.64898/2026.01.23.701347